diff --git a/windows/security/threat-protection/windows-sandbox/windows-sandbox-overview.md b/windows/security/threat-protection/windows-sandbox/windows-sandbox-overview.md
index ec211848d1..9aaeef5f2a 100644
--- a/windows/security/threat-protection/windows-sandbox/windows-sandbox-overview.md
+++ b/windows/security/threat-protection/windows-sandbox/windows-sandbox-overview.md
@@ -67,6 +67,8 @@ The following video provides an overview of Windows Sandbox.
 
 4. Locate and select **Windows Sandbox** on the Start menu to run it for the first time.
 
+   > [!NOTE]
+   > The Sandbox version of Windows will not respect the mouse settings of the host system, so if the host system is set to use a right-handed mouse, you will need to apply these settings inside the Sandbox manually.  
 
 ## Usage 
 1. Copy an executable file (and any other files needed to run the application) from the host and paste them into the **Windows Sandbox** window.